Enoxaparin binds to anti-thrombin III leading to inhibition of coagulation factors IIa and Xa.
It is indicated:
- for the prophylaxis of venous thromboembolic disorders in post-operative patients.
- for prophylaxis and treatment of venous thromboembolic disease due to acute illness, deep vein thrombosis and pulmonary embolism.
- for the treatment of unstable angina and non-Q-wave myocardial infarction, administered concurrently with aspirin.
- for the treatment of acute ST-segment Elevation Myocardial Infarction including patients to be managed medically or with subsequent Percutaneous Coronary Intervention in conjunction with thrombolytic drugs.
- for the prevention of thrombus formation in the extracorporeal circulation during haemodialysis.